Practical aspects in quality control of immunohistology

Wolf D. Kuhlmann

Division of Radiooncology, Deutsches Krebsforschungszentrum, 69120 Heidelberg, Germany

Laboratory Diagnostics & Cell Science, 56112 Lahnstein, Germany

Quality control is of great importance for reliable immunohistology. This can be only achieved by intensive work with a great number of control sets which include reagents as well as tissue preparations, otherwise artefacts (so-called false positive and false negative staining reactions) have to be expected. Some major problems are listed in tables which may be helpful in troubleshooting.